Regression of ETV6-NTRK3 Infantile Glioblastoma After First-Line Treatment With Larotrectinib
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Infantile Fibrosarcoma With NTRK3–ETV6 Fusion Successfully Treated With the Tropomyosin‐Related Kinase Inhibitor LOXO‐101
Infantile fibrosarcoma (IFS) is a rare pediatric cancer typically presenting in the first 2 years of life. Surgical resection is usually curative and chemotherapy is active against gross residual disease. However, when recurrences occur, therapeutic options are limited. We report a case of refractory IFS with constitutive activation of the tropomyosin-related kinase (TRK) signaling pathway from...
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ژورنال
عنوان ژورنال: JCO Precision Oncology
سال: 2020
ISSN: 2473-4284
DOI: 10.1200/po.20.00017